Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17238811 | 0.76 | THRB (0.33) | THRB | |
| SCHEMBL10079 | 0.73 | THRB (0.32) | THRB | |
| SCHEMBL288569 | 0.70 | THRB (0.30) | THRB | |
| SCHEMBL3771390 | 0.70 | THRB (0.30) | THRB | |
| SCHEMBL63977 | 0.70 | THRB (0.58) | THRB | |
| SCHEMBL10476348 | 0.70 | — | — | |
| SCHEMBL5963066 | 0.68 | THRB (0.55) | THRB | |
| SCHEMBL621694 | 0.68 | THRB (0.55) | THRB | |
| Water SCHEMBL22069810 | 0.68 | THRB (0.55) | THRB | |
| Hydrogen Peroxide SCHEMBL22401584 | 0.68 | THRB (0.41) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731788-B1 | PROLYL ENDOPEPTIDASE INHIBITORS | MERRELL PHARMA INC (US) | 2002-09-11 | — | — | EP | disclosed |
| US-5661167-A | MEMORY ENHANCEMENT, PREVENTING OR SLOWING THE AFFECT OF AMNESIA OR MEMORY DEFICITS | MERRELL PHARMACEUTICALS INC. (US) | 1997-08-26 | — | — | US | disclosed |
| EP-0731788-A1 | PROLYL ENDOPEPTIDASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-18 | — | — | EP | disclosed |
| WO-1995015310-A1 | PROLYL ENDOPEPTIDASE INHIBITORS | MERRELL PHARMACEUTICALS INC. (US) | 1995-06-08 | — | — | WO | disclosed |