Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7457109 | 0.80 | CRBN (0.51) | MCL1KMT2AKDM4ECA1CA2 | |
| SCHEMBL27744470 | 0.74 | KMT2A (0.49) | MCL1KMT2AKDM4EALDH1A1CA1 | |
| SCHEMBL10980130 | 0.74 | ALDH1A1 (0.64) | KMT2AALDH1A1TDP1MAPTL3MBTL1 | |
| SCHEMBL11241498 | 0.72 | GAA (0.55) | MCL1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL4732529 | 0.69 | DDB1 (0.59) | KDM4EALDH1A1TDP1HPGD | |
| SCHEMBL7521304 | 0.68 | KMT2A (0.41) | MCL1KMT2AKDM4EALDH1A1CA1 | |
| SCHEMBL29510552 | 0.67 | TLR9 (0.64) | MCL1KDM4EALDH1A1TDP1CA1 | |
| SCHEMBL3771981 | 0.67 | TLR9 (0.64) | MCL1KDM4EALDH1A1TDP1CA1 | |
| SCHEMBL840957 | 0.67 | KMT2A (0.49) | KMT2AKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL20881865 | 0.67 | KMT2A (0.52) | KMT2AKDM4EALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0715623-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1996-06-12 | — | — | EP | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |