SCHEMBL3771981

SCHEMBL3771981

N#Cc1ccccc1N1C(=O)C=CC1=O

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TLR9 Q9NR96 2/20 0.64
MGLL Q99685 12/20 0.53
FAAH O00519 3/20 0.48
ALDH1A1 P00352 1/20 0.44
HSP90AA1 P07900 1/20 0.44
PKM P14618 1/20 0.44
CCR6 P51684 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
TSHR P16473 1/20 0.40
MAPT P10636 1/20 0.40
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510552 1.00 TLR9 (0.64) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL508395 0.83 TLR9 (0.64) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL717690 0.82 TLR9 (0.61) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL11482027 0.80 NR1H3 (0.51) ALDH1A1KDM4E
SCHEMBL121404 0.79 TLR9 (1.00) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL29377102 0.79 TLR9 (1.00) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL718678 0.79 TLR9 (0.57) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL5943005 0.77 TLR9 (0.46) TLR9MGLLFAAH
SCHEMBL10584544 0.75 TLR9 (0.53) TLR9MGLLFAAHALDH1A1HSP90AA1
SCHEMBL13401408 0.73 ALDH1A1 (0.50) ALDH1A1NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
US-5096948-A Maleimide copolymer, hindered amine stabilizer, discoloration inhibition SANKYO COMPANY, LIMITED (JP) 1992-03-17 US claimed
CN-118151280-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151284-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151285-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151282-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151281-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-118151283-A Polarizing plate with retardation layer and image display device 日东电工株式会社 2024-06-07 CN disclosed
CN-114432301-B Covalent inhibitor derivative and application thereof in treatment of viral infection 北京大学 2024-05-31 CN disclosed
CN-118119867-A Polarizing plate with retardation layer and image display device comprising same 日东电工株式会社 2024-05-31 CN disclosed
CN-118103742-A Polarizing plate with retardation layer and image display device comprising same 日东电工株式会社 2024-05-28 CN disclosed
US-20060216436-A1 WIDE-VIEWING ANGLE COMPENSATION FILM AND TRANSMISSION TYPE LIQUID-CRYSTAL DISPLAY EMPLOYING THE SAME TOSOH CORPORATION (JP) 2006-09-28 US disclosed
US-7001967-B2 Resin with excellent heat resistance and dynamic characteristics, having negative birefringence and exhibiting a high refractive index and a high Abbe number, especially optical compensating members such as films, sheets and TOSOH CORPORATION (JP) 2006-02-21 US disclosed
CN-1569949-A Resin composition for optical film, optical film and process for producing the optical film TOSOH CORP (JP) 2005-01-26 CN disclosed
US-20040190138-A1 Resin composition for optical film, optical film and process for producing the optical film TOSOH CORPORATION (JP) 2004-09-30 US disclosed
US-20040063887-A1 Transparent heat-resistant resin optical material and film TOSOH CORPORATION (JP) 2004-04-01 US disclosed
EP-1403297-A1 Transparent heat-resistant resin optical material and film Tosoh Corporation (JP) 2004-03-31 EP disclosed
EP-0407113-B1 Resistant resin compositions SANKYO CO (JP) 1995-03-29 EP disclosed
US-5096948-A Maleimide copolymer, hindered amine stabilizer, discoloration inhibition SANKYO COMPANY, LIMITED (JP) 1992-03-17 US disclosed
EP-0407113-A1 Resistant resin compositions Sankyo Company Limited (JP) 1991-01-09 EP disclosed