Trolamine

Trolamine

SCHEMBL740171

CC(C)O.CC(C)O.OCCN(CCO)CCO.OCCN(CCO)CCO.[Ti]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KDM4E B2RXH2 2/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL27728576 1.00 MAPT (0.40) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL27571328 1.00 MAPT (0.40) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL27756311 0.97 MAPT (0.42) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL6682064 0.97 MAPT (0.42) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL6455111 0.97 MAPT (0.42) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL11507708 0.94 MAPT (0.40) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL8515537 0.90 MAPT (0.42) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL8769747 0.85 MAPT (0.38) MAPTTDP1CYP1A2CYP2C9HPGD
Trolamine SCHEMBL8385039 0.85 TDP1 (0.59) MAPTALDH1A1LMNATDP1CYP1A2
Trolamine SCHEMBL29008328 0.83 MAPT (0.39) MAPTCYP1A2CYP2C9HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384194-B2 Reactive adhesives based on block copolymers EVONIK OPERATIONS GMBH (DE) 2022-07-12 US disclosed
US-20200377641-A1 REACTIVE ADHESIVES BASED ON BLOCK COPOLYMERS EVONIK OPERATIONS GMBH (DE) 2020-12-03 US disclosed
EP-3480231-A1 REACTIVE ADHESIVES BASED ON BLOCK COPOLYMERS Evonik Degussa GmbH (DE) 2019-05-08 EP disclosed
US-8136596-B2 Methods of using water-superabsorbent polymers to reduce heat transfer BAKER HUGHES INCORPORATED (US) 2012-03-20 US disclosed
US-20100233375-A1 Methods of Using Water-Superabsorbent Polymers to Reduce Heat Transfer BAKER HUGHES INCORPORATED 2010-09-16 US disclosed
US-7762332-B2 Method of using water-superabsorbent polymer in production tubing and pipes BJ SERVICES COMPANY LLC (US) 2010-07-27 US disclosed
US-7713917-B2 Thermal insulation compositions containing organic solvent and gelling agent and methods of using the same BJ SERVICES COMPANY (US) 2010-05-11 US disclosed
US-7395863-B2 Method of treating a subterranean formation with an oil-based composition containing a polysaccharide-based water-superabsorbent material BJ SERVICES COMPANY (US) 2008-07-08 US disclosed
US-20080085843-A1 Well treating compositions containing water-superabsorbent polymers and method of using the same BJ SERVICES COMPANY 2008-04-10 US disclosed
US-7316275-B2 Well treating compositions containing water superabsorbent material and method of using the same BJ SERVICES COMPANY (US) 2008-01-08 US disclosed
US-7306039-B2 Methods of using crosslinkable compositions BJ SERVICES COMPANY (US) 2007-12-11 US disclosed
WO-2007133477-A1 THERMAL INSULATION COMPOSITIONS CONTAINING ORGANIC SOLVENT AND GELLING AGENT AND METHODS OF USING THE SAME BJ SERVICES COMPANY (US) 2007-11-22 WO disclosed
US-20070259791-A1 Thermal insulation compositions containing organic solvent and gelling agent and methods of using the same BJ SERVICES COMPANY 2007-11-08 US disclosed
US-20070167542-A1 Method of using water-superabsorbent polymer in production tubing and pipes BJ SERVICES COMPANY 2007-07-19 US disclosed
US-20060211580-A1 Well treating compositions containing water superabsorbent material and method of using the same BJ SERVICES COMPANY (US) 2006-09-21 US disclosed
US-20050038199-A1 Crosslinkable thermal insulating compositions and methods of using the same BAKER HUGHES, A GE COMPANY, LLC 2005-02-17 US disclosed
US-20040059054-A1 Compositions for thermal insulation and methods of using the same BAKER HUGHES, A GE COMPANY, LLC 2004-03-25 US disclosed
WO-2004025076-A1 COMPOSITIONS FOR THERMAL INSULATION AND METHODS OF USING THE SAME BJ SERVICES COMPANY (US) 2004-03-25 WO disclosed