Trolamine

Trolamine

SCHEMBL8515537

CC(O)O.OCCN(CCO)CCO

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.42
TDP1 Q9NUW8 1/20 0.39
HPGD P15428 2/20 0.36
MAPK1 P28482 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 3/20 0.33
TSHR P16473 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALOX15 P16050 1/20 0.33
ALDH1A1 P00352 3/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL27756311 0.93 MAPT (0.42) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL6455111 0.93 MAPT (0.42) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL6682064 0.93 MAPT (0.42) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL27571328 0.90 MAPT (0.40) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL740171 0.90 MAPT (0.40) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL11507708 0.90 MAPT (0.40) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL27728576 0.90 MAPT (0.40) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL8385039 0.88 TDP1 (0.59) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL8769747 0.88 MAPT (0.38) MAPTTDP1HPGDMAPK1CYP1A2
Trolamine SCHEMBL29008328 0.86 MAPT (0.39) MAPTHPGDMAPK1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2642973-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP Assets B.V. (NL) 2013-10-02 EP disclosed
WO-2012069362-A1 COSMETIC COMPOSITION FOR SKIN WHITENING COMPRISING RESVERATROL DSM IP ASSETS B.V. (NL) 2012-05-31 WO disclosed