Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | F10 | P00742 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358735 | 0.87 | PRSS1 (0.67) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL14629787 | 0.84 | PRSS1 (0.68) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24358796 | 0.83 | PRSS1 (0.71) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL28277477 | 0.83 | PRSS1 (0.61) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL14714355 | 0.82 | PRSS1 (0.69) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL289137 | 0.79 | F10 (0.57) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL28278911 | 0.79 | PRSS1 (0.65) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL288751 | 0.78 | F10 (0.56) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL7442925 | 0.77 | PRSS1 (0.65) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL9671457 | 0.77 | FOLH1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994000424-A1 | PHENYL AMIDINE ALKANOIC ACIDS AND LACTONES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-01-06 | — | — | WO | disclosed |