Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.61 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.61 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.61 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28278911 | 0.89 | PRSS1 (0.65) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24358735 | 0.87 | PRSS1 (0.67) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL14629787 | 0.84 | PRSS1 (0.68) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24358796 | 0.83 | PRSS1 (0.71) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL7897894 | 0.83 | LPL (0.46) | SPHK2SPHK1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5194309 | 0.83 | SPHK2 (0.52) | SPHK2SPHK1 | |
| SCHEMBL7401747 | 0.83 | PRSS1 (0.61) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL6954993 | 0.82 | SPHK2 (0.49) | PRSS1PRSS2PRSS3LOXL2SPHK2 | |
| SCHEMBL1696803 | 0.82 | PRSS1 (0.69) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL16951379 | 0.80 | LPL (0.50) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109468659-A | The method of room temperature synthesizing benzimidazole under the conditions of electrocatalytic method water phase | 云南师范大学 | 2019-03-15 | — | — | CN | disclosed |
| CN-109456273-A | The method of benzenecarboximidamide class compound synthesis benzimidazole compound is used in microwave method water phase | 云南师范大学 | 2019-03-12 | — | — | CN | disclosed |