Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.69 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.69 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.69 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.69 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 7/20 | 0.53 |
| ▸ | PLG | P00747 | 2/20 | 0.52 |
| ▸ | C1S | P09871 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401747 | 0.82 | PRSS1 (0.61) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24358796 | 0.82 | PRSS1 (0.71) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8542393 | 0.82 | PRSS1 (1.00) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL4078620 | 0.82 | LOXL2 (1.00) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL1696803 | 0.80 | PRSS1 (0.69) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL1634149 | 0.80 | PARP1 (0.53) | F10 | |
| Hydrochloric Acid SCHEMBL3666539 | 0.80 | LOXL2 (0.96) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL24358735 | 0.78 | PRSS1 (0.67) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL15547311 | 0.78 | PRSS1 (0.70) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL28278911 | 0.77 | PRSS1 (0.65) | PRSS1PRSS2PRSS3LOXL2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560962-A1 | INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS | Janssen Pharmaceutica NV (BE) | 2013-02-27 | — | — | EP | disclosed |