Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564798 | 0.87 | KDM4E (0.60) | ALDH1A1TDP1KDM4EHPGDPTGDR2 | |
| SCHEMBL8634758 | 0.84 | CNR2 (0.51) | ALDH1A1KDM4ESMN1; SMN2POLBCNR2 | |
| SCHEMBL7905505 | 0.83 | CNR2 (0.54) | ALDH1A1KDM4EHPGDL3MBTL1GLA | |
| SCHEMBL30147524 | 0.83 | MAPT (0.65) | ALDH1A1TDP1L3MBTL1SMN1; SMN2CNR2 | |
| SCHEMBL18428699 | 0.83 | MAPT (0.65) | ALDH1A1TDP1L3MBTL1SMN1; SMN2CNR2 | |
| SCHEMBL10747304 | 0.81 | POLB (0.71) | ALDH1A1TDP1KDM4EHPGDPTGDR2 | |
| SCHEMBL13576752 | 0.81 | IDO1 (0.58) | ALDH1A1KDM4EHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL10544032 | 0.80 | GSTP1 (0.66) | ALDH1A1TDP1KDM4EHPGDPTGDR2 | |
| SCHEMBL4006491 | 0.80 | LMNA (0.64) | ALDH1A1TDP1KDM4EHPGDPTGDR2 | |
| SCHEMBL13209708 | 0.79 | LMNA (0.51) | ALDH1A1KDM4EL3MBTL1SMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |
| US-4195093-A | DIURETIC AND URICOSURIC AGENTS | ALBERT ROLLAND S.A. (FR) | 1980-03-25 | — | — | US | disclosed |