Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581702 | 0.88 | CDC25B (0.52) | CNR2CNR1HTTSMN1; SMN2PLK1 | |
| SCHEMBL7401823 | 0.84 | ALDH1A1 (0.57) | CNR2CNR1SMN1; SMN2HPGDSKDM4E | |
| SCHEMBL7394786 | 0.84 | HPGDS (0.69) | CNR2CNR1HTTSMN1; SMN2PLK1 | |
| SCHEMBL10900892 | 0.83 | CASP3 (0.47) | CNR2CNR1HTTSMN1; SMN2KDM4E | |
| SCHEMBL10898603 | 0.81 | IDO1 (0.54) | CNR2CNR1HTTSMN1; SMN2KDM4E | |
| SCHEMBL10903024 | 0.81 | CASP3 (0.61) | HTTSMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL11286223 | 0.81 | LMNA (0.60) | HTTSMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL7905505 | 0.81 | CNR2 (0.54) | CNR2CNR1PLK1HPGDSKDM4E | |
| SCHEMBL29938478 | 0.81 | LMNA (0.60) | HTTSMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL13209708 | 0.80 | LMNA (0.51) | CNR2CNR1HTTSMN1; SMN2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753659-A | ANTICOAGULANTS FOR BLOOD DISORDER, CARDIOVASCULAR DISORDER, THROMBOSIS, | ZENECA LIMITED (GB) | 1998-05-19 | — | — | US | disclosed |
| US-5750754-A | TERTIARY BUTYL 3-METHYL-4-SUBSTITUTED BUTYRATE; CHEMICAL INTERMEDIATES FOR ANTICAOGULANT DRUGS | ZENECA LIMITED (GB) | 1998-05-12 | — | — | US | disclosed |
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |