Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 8/20 | 0.47 |
| ▸ | THRB | P10828 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399025 | 0.86 | KMT2A (0.43) | TBXA2RTHRATHRBHAO1GSK3B | |
| SCHEMBL7399274 | 0.85 | TBXA2R (0.52) | TBXA2RTBXAS1THRATHRBL3MBTL1 | |
| SCHEMBL11105772 | 0.80 | RARB (0.57) | TBXA2RTBXAS1L3MBTL1HAO1 | |
| SCHEMBL3011724 | 0.78 | THRA (0.66) | THRATHRBHAO1PLK1GSK3B | |
| SCHEMBL7404753 | 0.78 | THRA (0.62) | THRAGSK3BLMNASMN1; SMN2 | |
| SCHEMBL6626226 | 0.77 | MEN1 (0.61) | TBXA2RTBXAS1L3MBTL1NPC1RAB9A | |
| SCHEMBL638654 | 0.77 | THRA (0.73) | THRATHRBHAO1 | |
| SCHEMBL5187970 | 0.76 | MEN1 (0.44) | TBXA2RTBXAS1L3MBTL1NPC1RAB9A | |
| SCHEMBL8984247 | 0.75 | THRA (0.77) | THRATHRBHAO1 | |
| SCHEMBL7736637 | 0.75 | THRA (0.77) | THRATHRBHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |