Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.77 |
| ▸ | THRB | P10828 | 12/20 | 0.77 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.65 |
| ▸ | RARB | P10826 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15174539 | 1.00 | THRA (0.77) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL15186439 | 1.00 | THRA (0.77) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL8984157 | 1.00 | THRA (0.77) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL8388153 | 1.00 | THRA (0.77) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL3929949 | 1.00 | THRA (0.77) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL8984247 | 1.00 | THRA (0.77) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL638654 | 0.98 | THRA (0.73) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL11110027 | 0.95 | THRA (0.70) | THRATHRBHAO1RARBMEN1 | |
| SCHEMBL3011724 | 0.93 | THRA (0.66) | THRATHRBHAO1RARBALDH1A1 | |
| SCHEMBL8205823 | 0.88 | RARB (0.68) | THRATHRBHAO1RARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403172-B1 | 6-HEXYLOXY-3-FLUORO-2-(4-HEXYLPHENYL) BENZO(B)THIOPHENE AS FERROELECTRIC SWITCHES OR DISPLAYING DEVICES; DIELECTRIC ANISOTROPY | CLARIANT INTERNATIONAL LTD. (CH) | 2002-06-11 | — | — | US | disclosed |
| EP-0339252-B1 | 2,5-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same | DAINIPPON INK & CHEMICALS (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5128472-A | Electrooptical display materials, ferroelectric display | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-4997942-A | 2,4-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same | DAINIPPON INK AND CHEMICAL, INC. (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0339252-A2 | 2,5-disubstituted pyrazine derivatives, pyrimidine derivatives, and liquid crystal containing the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1989-11-02 | — | — | EP | disclosed |