Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399145 | 0.89 | GPR119 (0.56) | GPR119CHEK2 | |
| SCHEMBL7402974 | 0.87 | GPR119 (0.64) | GPR119MAPTALDH1A1CHEK2 | |
| SCHEMBL7376662 | 0.86 | GPR119 (0.70) | GPR119ALDH1A1CHEK2 | |
| SCHEMBL30750710 | 0.85 | GPR119 (0.54) | GPR119MAPTALDH1A1RAB9ACHEK2 | |
| SCHEMBL240683 | 0.84 | GPR119 (0.61) | GPR119ALDH1A1CHEK2PDE4APDE4B | |
| SCHEMBL3741314 | 0.83 | GPR119 (0.53) | GPR119ALDH1A1 | |
| SCHEMBL29716457 | 0.83 | GPR119 (0.53) | GPR119MAPT | |
| SCHEMBL21906814 | 0.83 | GPR119 (0.51) | GPR119ALDH1A1CHEK2 | |
| SCHEMBL241130 | 0.83 | GPR119 (0.59) | GPR119ALDH1A1CHEK2 | |
| SCHEMBL30750614 | 0.83 | GPR119 (0.52) | GPR119MAPTALDH1A1RAB9ACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |