Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401949 | 0.89 | GPR119 (0.54) | GPR119CHEK2 | |
| SCHEMBL30750710 | 0.87 | GPR119 (0.54) | GPR119CHEK2 | |
| SCHEMBL16385072 | 0.86 | GPR119 (0.67) | GPR119CHEK2KDM4EPKM | |
| SCHEMBL29716457 | 0.85 | GPR119 (0.53) | GPR119 | |
| SCHEMBL3741314 | 0.85 | GPR119 (0.53) | GPR119 | |
| SCHEMBL1575733 | 0.85 | GPR119 (0.72) | GPR119CHEK2KDM4EPKM | |
| SCHEMBL30750539 | 0.84 | GPR119 (0.52) | GPR119CHEK2 | |
| SCHEMBL30750614 | 0.84 | GPR119 (0.52) | GPR119CHEK2 | |
| SCHEMBL30750774 | 0.84 | ALDH1A1 (0.56) | GPR119KMT2AKDM4E | |
| SCHEMBL1649132 | 0.83 | GPR119 (0.64) | GPR119CHEK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648368-A | ANTICOAGULANTS | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| WO-1994012181-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |