Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401996 | 1.00 | PTGS1 (0.35) | PTGS1FAAHNR1I2PGRADORA3 | |
| SCHEMBL6441479 | 0.82 | FAAH (0.33) | FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6441473 | 0.82 | FAAH (0.33) | FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7394585 | 0.80 | TSHR (0.32) | TSHR | |
| SCHEMBL12749364 | 0.80 | CYP1A2 (0.32) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8765629 | 0.77 | HCAR2 (0.46) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL4412 | 0.77 | — | — | |
| SCHEMBL28285089 | 0.75 | — | — | |
| SCHEMBL8961872 | 0.75 | PTGS1 (0.39) | PTGS1NR1I2PGRADORA3PTGS2 | |
| SCHEMBL5836235 | 0.74 | TTR (0.40) | CYP1A2CYP2C9CYP2C19ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000972-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-01-23 | — | — | WO | disclosed |