Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441479 | 1.00 | FAAH (0.33) | FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7401995 | 0.82 | PTGS1 (0.35) | FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7401996 | 0.82 | PTGS1 (0.35) | FAAHCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12749364 | 0.82 | CYP1A2 (0.32) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7394585 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL7394588 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL8961867 | 0.76 | — | — | |
| SCHEMBL28417828 | 0.76 | HCAR2 (0.43) | — | |
| SCHEMBL5836235 | 0.76 | TTR (0.40) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7706439 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189874-B1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | LILLY SA (ES) | 2005-01-26 | — | — | EP | disclosed |
| US-6504052-B1 | 2-carboxycyclopropyl glycine derivatives, used as agonists of glutamate receptors for prophylaxis of psychological and nervous system disorders; anxiolytics; antidepressants; drug abuse; anticonvulsant, analgesic and antiemetic agents | ELI LILLY AND COMPANY | 2003-01-07 | — | — | US | disclosed |
| EP-1189874-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | Lilly, S.A. (ES) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075102-A1 | EXCITATORY AMINO ACID RECEPTOR MODULATORS | LILLY, S.A. (ES) | 2000-12-14 | — | — | WO | disclosed |