Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.60 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | DPP3 | Q9NY33 | 3/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | NPY4R | P50391 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.49 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | EED | O75530 | 1/20 | 0.49 |
| ▸ | CCKBR | P32239 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396077 | 0.99 | MAGI3 (0.60) | MAGI3KISS1REDNRAERBB2IL23R | |
| SCHEMBL9068982 | 0.98 | MAGI3 (0.58) | MAGI3KISS1REDNRACAPN1CTSB | |
| SCHEMBL7399755 | 0.95 | MAGI3 (0.55) | MAGI3KISS1RERBB2DPP3CAPN1 | |
| SCHEMBL7402771 | 0.95 | KISS1R (0.57) | MAGI3KISS1REDNRAERBB2CAPN1 | |
| SCHEMBL7396073 | 0.94 | KISS1R (0.58) | MAGI3KISS1RERBB2CAPN1CTSB | |
| SCHEMBL7402113 | 0.94 | MAGI3 (0.56) | MAGI3KISS1RERBB2DPP3CAPN1 | |
| SCHEMBL30262151 | 0.87 | KISS1R (0.59) | MAGI3KISS1RNPY1RNPY2RNPY4R | |
| SCHEMBL38664590 | 0.85 | NPY1R (0.57) | MAGI3KISS1RIL23RNPY1RNPY2R | |
| SCHEMBL7400113 | 0.84 | CALCRL (0.51) | — | |
| SCHEMBL7400882 | 0.84 | EDNRA (0.71) | MAGI3KISS1REDNRAERBB2IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | claimed |
| US-5504070-A | ADMINISTERING OLIGOPEPTIDES, PHOSPHONATES AND MODIFIED AMINO ACIDS AS INHIBITORS | BERLEX LABORATORIES, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1993011154-A1 | INHIBITORS OF THE CONVERSION OF BIG ENDOTHELIN TO ENDOTHELIN | BERLEX LABORATORIES, INC. (US) | 1993-06-10 | — | — | WO | disclosed |