SCHEMBL7403195

SCHEMBL7403195

CNC(CCC(N)=O)C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.36
FNTB P49356 1/20 0.36
NOS1 P29475 2/20 0.35
NOS3 P29474 1/20 0.35
NOS2 P35228 1/20 0.35
BMP1 P13497 1/20 0.34
KMT2A Q03164 3/20 0.33
ALOX15 P16050 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
FOLH1 Q04609 1/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12267040 0.84 ANPEP (0.42) BMP1KMT2ACYP1A2FOLH1MEN1
SCHEMBL9086263 0.84 L3MBTL1 (0.37) KMT2AL3MBTL1CYP1A2CYP2C9CYP2C19
SCHEMBL22316568 0.84 ANPEP (0.42) BMP1KMT2ACYP1A2FOLH1MEN1
SCHEMBL5172322 0.84 ANPEP (0.42) BMP1KMT2ACYP1A2FOLH1MEN1
SCHEMBL11184897 0.83 CYP1A2 (0.46) FNTAFNTBCYP1A2CYP2C9CYP2C19
SCHEMBL29400405 0.83 FNTA (0.39) FNTAFNTBNOS1NOS3NOS2
SCHEMBL11103967 0.83 CYP1A2 (0.46) FNTAFNTBCYP1A2CYP2C9CYP2C19
SCHEMBL3241829 0.83 CYP1A2 (0.46) FNTAFNTBCYP1A2CYP2C9CYP2C19
SCHEMBL3400833 0.82 MEN1 (0.34) NOS1NOS3NOS2KMT2ACYP1A2
SCHEMBL7402242 0.82 MAOA (0.35) NOS1NOS3NOS2KMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4310093-A1 AMINO ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR TREATING HEPATITIS, COMPRISING SAME Prazertherapeutics Inc. (KR) 2024-01-24 EP disclosed
EP-0634998-B1 HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS BRITISH BIOTECH PHARM (GB) 1997-03-19 EP disclosed
US-5525629-A HYDROXAMIC ACID DERIVATIVES BRITISH BIO-TECHNOLOGY LIMITED (GB) 1996-06-11 US disclosed
EP-0634998-A1 HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS. BRITISH BIO TECHNOLOGY (GB) 1995-01-25 EP disclosed
WO-1993020047-A1 HYDROXAMIC ACID BASED COLLAGENASE AND CYTOKINE INHIBITORS BRITISH BIO-TECHNOLOGY LIMITED (GB) 1993-10-14 WO disclosed