Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.53 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.45 |
| ▸ | FES | P07332 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | MARK3 | P27448 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 6/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946884 | 0.86 | ITGB3 (0.55) | ITGB3ITGA2BSUCNR1ITGAVTBXAS1 | |
| SCHEMBL7393079 | 0.86 | FLT4 (0.41) | ITGB3ITGA2BFLT4CDK2FES | |
| SCHEMBL6946962 | 0.85 | ITGB3 (0.60) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL7386316 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BSUCNR1EPHX2 | |
| SCHEMBL4924076 | 0.85 | ITGB3 (0.56) | ITGB3ITGA2BSUCNR1ITGAVTBXAS1 | |
| SCHEMBL7403231 | 0.84 | ITGB3 (0.46) | ITGB3ITGA2BFLT4CDK2SUCNR1 | |
| SCHEMBL6950480 | 0.83 | ITGB3 (0.57) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL243197 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BSUCNR1ITGAVTBXAS1 | |
| SCHEMBL7386330 | 0.78 | EPHX2 (0.43) | ITGB3ITGA2BSUCNR1EPHX2 | |
| SCHEMBL9293681 | 0.77 | ITGB3 (0.54) | ITGB3ITGA2BEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | claimed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | claimed |
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | disclosed |