Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | FES | P07332 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | MARK3 | P27448 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 5/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947579 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BSUCNR1ITGAVTBXAS1 | |
| SCHEMBL6946972 | 0.85 | ITGB3 (0.53) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL4924109 | 0.84 | ITGB3 (0.52) | ITGB3ITGA2BSUCNR1ITGAVTBXAS1 | |
| SCHEMBL7403227 | 0.84 | ITGB3 (0.53) | ITGB3ITGA2BSUCNR1FLT4CDK2 | |
| SCHEMBL6950494 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL7386330 | 0.83 | EPHX2 (0.43) | ITGB3ITGA2BSUCNR1EPHX2 | |
| SCHEMBL7386316 | 0.79 | ITGB3 (0.59) | ITGB3ITGA2BSUCNR1EPHX2 | |
| SCHEMBL6948963 | 0.75 | ITGB3 (0.46) | ITGB3ITGA2BSUCNR1ITGAV | |
| SCHEMBL9293684 | 0.75 | TSHR (0.41) | EPHX2 | |
| SCHEMBL7391732 | 0.74 | ITGB3 (0.54) | ITGB3ITGA2BSUCNR1ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | claimed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | claimed |
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | disclosed |