Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | METAP1 | P53582 | 3/20 | 0.55 |
| ▸ | NCF1 | P14598 | 5/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402473 | 0.92 | MAPT (0.79) | MAPTMETAP1NCF1KDRMEN1 | |
| SCHEMBL8237815 | 0.89 | MAPT (1.00) | MAPTNCF1KDRMEN1KMT2A | |
| SCHEMBL7404796 | 0.85 | MAPT (0.58) | MAPTMETAP1NCF1KDRLMNA | |
| SCHEMBL7403964 | 0.83 | MAPT (0.54) | MAPTKDRMEN1KMT2ALMNA | |
| SCHEMBL7400283 | 0.77 | MAPT (0.58) | MAPTMETAP1KDRMEN1KMT2A | |
| SCHEMBL8605546 | 0.77 | MEN1 (0.48) | MAPTKDRMEN1KMT2ALMNA | |
| SCHEMBL7395642 | 0.73 | MAPT (0.52) | MAPTMEN1KMT2ALMNAPKM | |
| SCHEMBL7327928 | 0.73 | HRH3 (0.59) | MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL8229816 | 0.73 | NCF1 (0.76) | MAPTNCF1MEN1KMT2ALMNA | |
| SCHEMBL900155 | 0.72 | NCF1 (0.82) | MAPTNCF1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |