Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404796 | 0.89 | MAPT (0.58) | MAPTPDGFRBKDRALDH1A1LMNA | |
| SCHEMBL7402473 | 0.86 | MAPT (0.79) | MAPTKDRALDH1A1LMNAMETAP1 | |
| SCHEMBL7400458 | 0.80 | ALDH1A1 (0.42) | MAPTKDRALDH1A1LMNATSHR | |
| SCHEMBL7335436 | 0.79 | HRH3 (0.59) | MAPTALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL7398310 | 0.77 | MEN1 (0.49) | MAPTALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7403264 | 0.77 | MAPT (0.80) | MAPTKDRALDH1A1LMNAMETAP1 | |
| SCHEMBL7404640 | 0.76 | ALDH1A1 (0.45) | KDRALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7395642 | 0.75 | MAPT (0.52) | MAPTALDH1A1LMNATSHRKDM4E | |
| SCHEMBL8237815 | 0.73 | MAPT (1.00) | MAPTKDRALDH1A1LMNATSHR | |
| SCHEMBL7399086 | 0.72 | SLC22A12 (0.49) | MAPTPDGFRBALDH1A1METAP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563141-A | INHIBIT CELL ADHESION FOR EXAMPLE, PLATELET AGGRE GATION | ZENECA LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |