Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397902 | 0.97 | DRD4 (0.54) | DRD4SLC6A4POLBHTR1ADRD2 | |
| SCHEMBL8905952 | 0.89 | DRD4 (0.50) | DRD4SLC6A4POLBHTR1ADRD2 | |
| SCHEMBL7403454 | 0.85 | DRD4 (0.59) | DRD4SLC6A4POLBHTR1ADRD2 | |
| SCHEMBL7493712 | 0.82 | DRD4 (0.61) | DRD4SLC6A4POLBHTR1ADRD2 | |
| SCHEMBL27442371 | 0.81 | DRD4 (0.44) | DRD4SLC6A4HTR1ADRD2HRH3 | |
| SCHEMBL5633970 | 0.81 | CHKA (0.56) | POLBHRH3HDAC6KMT2AHSD17B10 | |
| SCHEMBL4541604 | 0.80 | DRD4 (0.57) | DRD4HDAC6KMT2AHSD17B10HDAC1 | |
| SCHEMBL9080516 | 0.80 | MEN1 (0.50) | DRD4SLC6A4POLBHTR1ADRD2 | |
| SCHEMBL8634749 | 0.80 | HRH3 (0.48) | DRD4SLC6A4POLBHRH3KMT2A | |
| Hydrochloric Acid SCHEMBL8838061 | 0.79 | HRH3 (0.53) | DRD2HRH3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691959-B1 | HETEROCYCLIC DERIVATIVES AS PLATELET AGGREGATION INHIBITORS | ZENECA LTD (GB) | 1998-07-22 | — | — | EP | disclosed |
| EP-0825184-A1 | Heterocyclic derivatives as platelet aggregation inhibitors | ZENECA LIMITED (GB) | 1998-02-25 | — | — | EP | disclosed |
| US-5556977-A | ANTIAGGLOMERANTS FOR CELLS, ANTICOAGULANTS, ANTIISCHEMIC AGENTS USING PYRIDINYLPIPERAZINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |
| EP-0690847-A1 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1996-01-10 | — | — | EP | disclosed |
| WO-1994022835-A2 | HETEROCYCLIC COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | disclosed |