Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7404178 | 1.00 | EPHX1 (0.38) | EPHX1ALOX5FDPSADH1ACES2 | |
| SCHEMBL6827765 | 0.83 | ALOX5 (0.45) | EPHX1ALOX5FDPSADH1ACES2 | |
| SCHEMBL22729195 | 0.80 | ALOX5 (0.43) | EPHX1ALOX5FDPSADH1ACES2 | |
| SCHEMBL3083216 | 0.78 | CES2 (0.41) | EPHX1ALOX5CES2CES1 | |
| SCHEMBL1957147 | 0.77 | ALOX5 (0.41) | EPHX1ALOX5FDPSADH1ACES2 | |
| SCHEMBL3069635 | 0.75 | ALOX5 (0.39) | EPHX1ALOX5FDPSADH1ACES2 | |
| SCHEMBL28496043 | 0.75 | ALOX5 (0.39) | EPHX1ALOX5FDPSADH1ACES2 | |
| SCHEMBL6235316 | 0.73 | ALOX5 (0.38) | EPHX1ALOX5FDPSADH1ACES2 | |
| SCHEMBL6242109 | 0.71 | ALOX5 (0.36) | EPHX1ALOX5ADH1A | |
| SCHEMBL7611692 | 0.71 | ALOX5 (0.37) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505322-A1 | Aminoguanidines | SANDOZ LTD. (CH) | 1992-09-23 | — | — | EP | disclosed |