Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 11/20 | 0.47 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209513 | 0.80 | MEN1 (0.49) | HPRT1PNPALDH1A1LMNA | |
| SCHEMBL21137628 | 0.77 | HPRT1 (0.49) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL21127785 | 0.74 | HPRT1 (0.48) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL9534973 | 0.72 | HPRT1 (0.47) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL1993930 | 0.71 | HPRT1 (0.63) | HPRT1PNPLMNA | |
| SCHEMBL1992701 | 0.70 | HPRT1 (0.54) | HPRT1PNPALDH1A1 | |
| SCHEMBL16276016 | 0.70 | HPRT1 (0.50) | HPRT1PNPALDH1A1LMNAALB | |
| SCHEMBL7398541 | 0.69 | HPRT1 (0.55) | HPRT1PNP | |
| SCHEMBL20782416 | 0.69 | HPRT1 (0.65) | HPRT1PNP | |
| SCHEMBL8791177 | 0.69 | HPRT1 (0.51) | HPRT1PNPALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004451-A2 | METHODS FOR STIMULATION OF SYNTHESIS OF SYNAPTOPHYSIN IN THE CENTRAL NERVOUS SYSTEM | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2002004449-A2 | METHODS FOR TREATMENT OF CONDITIONS AFFECTED BY ACTIVITY OF MULTIDRUG TRANSPORTERS | NEOTHERAPEUTICS, INC. (US) | 2002-01-17 | — | — | WO | disclosed |