Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | WEE1 | P30291 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412024 | 0.90 | WEE1 (0.50) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| SCHEMBL7412394 | 0.84 | SRC (0.43) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| Bromide SCHEMBL10733467 | 0.83 | SRC (0.42) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| Water SCHEMBL7408556 | 0.83 | SRC (0.42) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| SCHEMBL7418131 | 0.81 | KMO (0.41) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| Ethylamine SCHEMBL7408665 | 0.80 | SRC (0.43) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| SCHEMBL10743242 | 0.79 | KDM4E (0.46) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| SCHEMBL10964970 | 0.78 | KDM4E (0.48) | KDM4EHSD17B10POLBL3MBTL1ALDH1A1 | |
| SCHEMBL10745628 | 0.78 | KMO (0.53) | KMOKDM4EHSD17B10POLBL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10739573 | 0.77 | KDM4E (0.47) | KDM4EHSD17B10POLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631283-A | RENAL VASODILATORS, CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-23 | — | — | US | disclosed |
| US-4490374-A | CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0107398-A1 | Ortho substituted dihydroxy-2(1H)quinazolinone-1-alkanoic acids | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-05-02 | — | — | EP | disclosed |