Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.44 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740616 | 1.00 | ATM (0.49) | ATMCTSLFFAR1MMEL1TSHR | |
| SCHEMBL1519890 | 1.00 | ATM (0.49) | ATMCTSLFFAR1MMEL1TSHR | |
| SCHEMBL2550398 | 0.88 | ATM (0.48) | ATMCTSLTSHRAAK1CTSB | |
| SCHEMBL2550395 | 0.88 | ATM (0.48) | ATMCTSLTSHRAAK1CTSB | |
| SCHEMBL5757675 | 0.86 | ATM (0.47) | ATMCTSLTSHRAAK1CTSB | |
| SCHEMBL740780 | 0.86 | MME (0.56) | ATMCTSLMMEL1CTSBCTSS | |
| SCHEMBL5966601 | 0.86 | MME (0.56) | ATMCTSLMMEL1CTSBCTSS | |
| SCHEMBL740779 | 0.86 | MME (0.56) | ATMCTSLMMEL1CTSBCTSS | |
| SCHEMBL742227 | 0.84 | CTSL (0.62) | ATMCTSLMMEL1CTSBCTSS | |
| SCHEMBL742226 | 0.84 | CTSL (0.62) | ATMCTSLMMEL1CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |