Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | CTSS | P25774 | 2/20 | 0.56 |
| ▸ | CTSH | P09668 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | CTSC | P53634 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 7/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406168 | 1.00 | CTSB (0.56) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7406164 | 1.00 | CTSB (0.56) | CTSBCTSSCTSHCTSKCTSC | |
| Hydrochloric Acid SCHEMBL7362186 | 0.98 | CTSB (0.55) | CTSBCTSSCTSHCTSKCTSC | |
| Hydrochloric Acid SCHEMBL7362196 | 0.98 | CTSB (0.55) | CTSBCTSSCTSHCTSKCTSC | |
| Hydrochloric Acid SCHEMBL7362193 | 0.98 | CTSB (0.55) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL8696147 | 0.86 | CTSB (0.51) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL8696155 | 0.86 | CTSB (0.51) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7411452 | 0.85 | CTSB (0.44) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7411448 | 0.85 | CTSB (0.44) | CTSBCTSSCTSHCTSKCTSC | |
| SCHEMBL7411443 | 0.85 | CTSB (0.44) | CTSBCTSSCTSHCTSKCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817778-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030353-A1 | REVERSIBLE PROTEASE INHIBITORS | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-10-03 | — | — | WO | disclosed |