SCHEMBL7406299

SCHEMBL7406299

Cc1oc(C(C)(C)C)cc(=O)c1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
ALOX15 P16050 1/20 0.46
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
PKM P14618 1/20 0.37
TP53 P04637 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
STS P08842 1/20 0.36
TSHR P16473 3/20 0.36
ALDH1A1 P00352 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
LMNA P02545 2/20 0.36
GAA P10253 1/20 0.36
ALDH1A2 O94788 1/20 0.34
ALDH2 P05091 1/20 0.34
ALDH1B1 P30837 1/20 0.34
ALDH1A3 P47895 1/20 0.34
MAPT P10636 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820796 0.70 L3MBTL1 (0.48) L3MBTL1ALOX15KMT2AMEN1PKM
SCHEMBL13295080 0.70 L3MBTL1 (0.48) L3MBTL1ALOX15KMT2AMEN1PKM
SCHEMBL10787662 0.69 ALOX15 (0.44) L3MBTL1ALOX15KMT2AMEN1PKM
SCHEMBL21718795 0.68 L3MBTL1 (0.47) L3MBTL1ALOX15KMT2AMEN1PKM
SCHEMBL3955737 0.68 L3MBTL1 (0.47) L3MBTL1ALOX15KMT2AMEN1PKM
SCHEMBL3102495 0.68 L3MBTL1 (0.47) L3MBTL1ALOX15KMT2AMEN1PKM
SCHEMBL572624 0.67 L3MBTL1 (0.70) L3MBTL1ALOX15KMT2AMEN1PKM
SCHEMBL7619043 0.67 ALOX15 (0.43) L3MBTL1ALOX15KMT2AMEN1STS
SCHEMBL13692387 0.67 L3MBTL1 (0.70) L3MBTL1KMT2AMEN1PKMTP53
SCHEMBL804843 0.67 NQO1 (0.61) L3MBTL1ALOX15KMT2AMEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828758-B1 CHIMERIC FATTY BODY-PRO-GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY THERATECHNOLOGIES INC (CA) 2001-08-29 EP disclosed
US-5939386-A GROWTH HORMONE (GH) OR SOMATOTROPIN, SECRETED BY THE PITUITARY GLAND CONSTITUTE A FAMILY OF HORMONES THERATECHNOLOGIES INC. (CA) 1999-08-17 US disclosed
US-5861379-A POLYPEPTIDE N-ANCHORED WITH HYDROPHOBIC TAIL AND AMINATED AT CARBOXYL END; TREATING SOMATOTROPIN DEFICIENCIES; ANABOLIC AGENTS THERATECHNOLOGIES INC. (CA) 1999-01-19 US disclosed
EP-0828758-A1 CHIMERIC FATTY BODY-PRO-GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY THERATECHNOLOGIES INC. (CA) 1998-03-18 EP disclosed
WO-1996037514-A1 CHIMERIC FATTY BODY-PRO-GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY THERATECHNOLOGIES INC. (CA) 1996-11-28 WO disclosed