Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 5/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406512 | 0.91 | HPGD (0.79) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL2206850 | 0.86 | TP53 (0.51) | HPGDTDP1ALDH1A1PARP1 | |
| Hydrochloric Acid SCHEMBL3355966 | 0.85 | TP53 (0.50) | HPGDTDP1ALDH1A1PARP1 | |
| Hydrochloric Acid SCHEMBL3352609 | 0.85 | TP53 (0.50) | HPGDTDP1ALDH1A1PARP1 | |
| SCHEMBL7314304 | 0.84 | HSP90AA1 (0.54) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL29386132 | 0.84 | HPGD (0.69) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL2566192 | 0.84 | HPGD (0.69) | HPGDTDP1ALDH1A1LMNATSHR | |
| SCHEMBL20881904 | 0.83 | HPGD (0.48) | HPGDTDP1ALDH1A1LMNATSHR | |
| Acetic Acid SCHEMBL6139768 | 0.82 | TP53 (0.47) | HPGDTDP1ALDH1A1PARP1 | |
| SCHEMBL6675903 | 0.82 | HPGD (0.56) | HPGDTDP1ALDH1A1TSHRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| CN-105530812-B | Insect repellent and insect repelling method | 理研香料控股株式会社 | 2020-01-14 | — | — | CN | disclosed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | ICAGEN, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-7223782-B2 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | SCN3A, TRPV3, HCN3 | HPGD 1358/4885TDP1 3631/4885ALDH1A1 3589/4885 |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | SCN3A, TRPV3, HCN3 | HPGD 1358/4885TDP1 3631/4885ALDH1A1 3589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.