Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275896 | 0.95 | HTR1A (0.47) | HTR1AKDM4ETP53POLBHRH3 | |
| SCHEMBL2713004 | 0.89 | KDM4E (0.49) | HTR1AKDM4ETP53POLBCYP11B2 | |
| SCHEMBL7282701 | 0.85 | KDM4E (0.45) | HTR1AKDM4ETP53POLBHRH3 | |
| Bicarbonate SCHEMBL8574872 | 0.81 | CA1 (0.42) | HTR1AKDM4ETP53POLBCYP11B2 | |
| Bicarbonate SCHEMBL8574878 | 0.81 | CA1 (0.42) | HTR1AKDM4ETP53POLBCYP11B2 | |
| SCHEMBL14491992 | 0.80 | DDB1 (0.53) | HTR1AKDM4ETP53POLBCMA1 | |
| Bicarbonate SCHEMBL8574870 | 0.80 | CA1 (0.41) | HTR1AKDM4ETP53POLBELANE | |
| SCHEMBL8286230 | 0.79 | SMN1; SMN2 (0.54) | KDM4EPOLBELANECMA1CTSG | |
| Hydrochloric Acid SCHEMBL5314439 | 0.79 | DDB1 (0.51) | HTR1AKDM4ETP53POLBCMA1 | |
| SCHEMBL1259982 | 0.79 | ALDH1A1 (0.46) | KDM4ETP53POLBCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715623-B1 | PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5489594-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5430043-A | Platelet aggregation inhibitors | G. D. SEARLE & CO. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995006038-A1 | PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |