Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35185 | 0.80 | MEN1 (0.65) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29399627 | 0.80 | MEN1 (0.65) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6398896 | 0.79 | APOBEC3G (0.52) | LMNAALDH1A1KMT2ACA1CA2 | |
| SCHEMBL11586735 | 0.78 | KMT2A (0.51) | LMNAALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8973992 | 0.78 | ALDH1A1 (0.57) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10250146 | 0.77 | LMNA (1.00) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6417389 | 0.75 | LMNA (0.62) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20573986 | 0.75 | ALDH1A1 (0.68) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL1000532 | 0.74 | MAPT (0.60) | LMNAALDH1A1KMT2AKDM4ETSHR | |
| SCHEMBL28004 | 0.74 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2AKR1C3AKR1C1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074786-A1 | HETEROBIARYLSULPHONAMIDES AND THEIR USE AS PDE 7 INHIBITORS | DARWIN DISCOVERY LIMITED (GB) | 2001-10-11 | — | — | WO | disclosed |