Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572558 | 0.84 | MEN1 (0.58) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL7445918 | 0.82 | MEN1 (0.86) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL7855886 | 0.82 | MEN1 (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| Hydrogen Sulfide SCHEMBL28029146 | 0.81 | MEN1 (0.83) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL23169604 | 0.80 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL30892695 | 0.80 | MEN1 (0.74) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL6677412 | 0.79 | MEN1 (1.00) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL30463435 | 0.79 | MEN1 (1.00) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| Hydrochloric Acid SCHEMBL20578422 | 0.77 | MEN1 (0.96) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 | |
| SCHEMBL8572766 | 0.77 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921800-A4 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL MYERS SQUIBB CO (US) | 2000-12-06 | — | — | EP | disclosed |
| EP-0921800-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997029748-A1 | SUBSTITUTED BIPHENYL ISOXAZOLE SULFONAMIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-21 | — | — | WO | disclosed |