Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SCN1A | P35498 | 3/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30463435 | 1.00 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| Hydrochloric Acid SCHEMBL20578422 | 0.98 | MEN1 (0.96) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL7445918 | 0.92 | MEN1 (0.86) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| Hydrogen Sulfide SCHEMBL28029146 | 0.91 | MEN1 (0.83) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL3760398 | 0.85 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL23169604 | 0.85 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL30892695 | 0.85 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL30603819 | 0.85 | KMT2A (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL5318803 | 0.85 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL15849713 | 0.85 | MEN1 (0.73) | MEN1KMT2ASMN1; SMN2ALDH1A1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072850-B | 3-sulfonyl-5-aminopyridine-2, 4-diol APJ agonists | 百时美施贵宝公司 | 2023-07-21 | — | — | CN | claimed |
| JP-57200338-A | — | — | None | — | — | JP | disclosed |
| US-20240083857-A1 | 2-Methyl-Quinazolines | Bayer Pharma AG (DE) | 2024-03-14 | — | — | US | disclosed |
| CN-110072850-B | 3-sulfonyl-5-aminopyridine-2, 4-diol APJ agonists | 百时美施贵宝公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-112243439-A | Pyrrolo [2,3-B ] pyridines or pyrrolo [2,3-B ] pyrazines as HPK1 inhibitors and uses thereof | 百济神州有限公司 | 2021-01-19 | — | — | CN | disclosed |
| CN-112118841-A | Spirocyclic ROR-gamma modulators | 爱思凯利尔生物科学私人有限责任公司 | 2020-12-22 | — | — | CN | disclosed |
| EP-3710159-A1 | CATALYST COMPONENTS FOR PROPYLENE POLYMERIZATION | W. R. Grace & Co. - Conn. (US) | 2020-09-23 | — | — | EP | disclosed |
| CN-105073745-B | glucosylceramide synthase inhibitors | 建新公司 | 2018-06-29 | — | — | CN | disclosed |
| US-20120302752-A1 | Compounds and Methods for Catalytic Directed ortho Substitution of Aromatic Amides and Esters | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-11-29 | — | — | US | disclosed |
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | US | disclosed |
| CN-100553929-C | Improved vehicle structural members and methods of making the same | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-10-28 | — | — | CN | disclosed |
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |
| US-4473709-A | Pyrethroid intermediates and process | FMC CORPORATION (US) | 1984-09-25 | — | — | US | disclosed |
| JP-S57200338-A | PREPARATION OF AMIDE | MITSUBISHI PETROCHEM CO LTD | 1982-12-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240083857-A1 | 2-Methyl-Quinazolines | NRAS, KRAS, KSR2 | MEN1 403/4885KMT2A 834/4885SMN1; SMN2 3477/4885 |
| US-20120302752-A1 | Compounds and Methods for Catalytic Directed ortho Substitution of Aromatic Amides and Esters | DDC, AOC2, AOC3 | MEN1 4327/4885KMT2A 1382/4885SMN1; SMN2 3846/4885 |
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SERPINB1, CTSC, HPN | MEN1 4685/4885KMT2A 4291/4885SMN1; SMN2 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.