Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 5/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.39 |
| ▸ | BRAF | P15056 | 7/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405346 | 0.82 | CHEK2 (0.49) | F10PRSS1PRSS2PRSS3GFER | |
| SCHEMBL7407336 | 0.80 | F2 (0.47) | CDK1CDK2F10PRSS1PRSS2 | |
| SCHEMBL3830602 | 0.77 | F10 (0.47) | F10PRSS1PRSS2PRSS3F2 | |
| SCHEMBL7407314 | 0.76 | KDM4E (0.44) | F10ALDH1A1 | |
| SCHEMBL7403871 | 0.74 | F10 (0.46) | CDK1CDK2F10PRSS1PRSS2 | |
| SCHEMBL7407064 | 0.73 | F10 (0.50) | CDK1CDK2F10PRSS1PRSS2 | |
| SCHEMBL7404851 | 0.73 | MLKL (0.45) | F10PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7405075 | 0.73 | F2 (0.44) | F10PRSS1PRSS2PRSS3GFER | |
| SCHEMBL7403000 | 0.71 | F10 (0.58) | F10PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL14599604 | 0.71 | ALDH1A1 (0.59) | CDK1CDK2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |