Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159543 | 0.92 | RAB9A (0.56) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| Fostedil SCHEMBL612913 | 0.91 | KDM4E (0.53) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| Fostedil SCHEMBL29387277 | 0.91 | KDM4E (0.53) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| SCHEMBL11404850 | 0.89 | F2RL3 (0.43) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| Fostedil SCHEMBL11166196 | 0.83 | RAB9A (0.46) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| SCHEMBL10707569 | 0.82 | RAB9A (0.54) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| SCHEMBL11160844 | 0.81 | RAB9A (0.51) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| SCHEMBL11153617 | 0.81 | RAB9A (0.59) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| SCHEMBL11441345 | 0.81 | RAB9A (0.45) | RAB9AMAPTNOD2PAX8L3MBTL1 | |
| SCHEMBL11155474 | 0.80 | ATP4A (0.57) | RAB9AMAPTNOD2PAX8L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434162-A | VASODILATOR, ANGINA PECTORIS, HYPOTENSIVE AGENTS | KANEBO, LTD. (JP) | 1984-02-28 | — | — | US | claimed |
| EP-0638581-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-4434162-A | VASODILATOR, ANGINA PECTORIS, HYPOTENSIVE AGENTS | KANEBO, LTD. (JP) | 1984-02-28 | — | — | US | disclosed |