Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513404 | 0.81 | TSHR (0.47) | F10PRKAG1PRKAA2PRKAB1PRKAA1 | |
| SCHEMBL38661086 | 0.81 | IDO1 (0.59) | EGLN1F10APEX1NPSR1ALDH1A1 | |
| SCHEMBL31716315 | 0.80 | PRKAG1 (0.72) | EGLN1F10PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL31735460 | 0.80 | MEN1 (0.60) | EGLN1F10PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL16810842 | 0.79 | TDP1 (0.54) | EGLN1F10PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL20320868 | 0.78 | TPH1 (0.45) | EGLN1KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20495186 | 0.76 | KDM4E (0.43) | PRKAG1PRKAA2PRKAB1KDM4EALDH1A1 | |
| SCHEMBL12264335 | 0.75 | GAA (0.62) | F10KDM4EPDE10AALDH1A1CYP1A2 | |
| SCHEMBL22584708 | 0.75 | CACNA1H (0.62) | EGLN1F10KDM4EPDE10AALDH1A1 | |
| SCHEMBL1941487 | 0.75 | PDE10A (0.49) | F10PRKAG1PRKAA2PRKAB1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999026932-A1 | BY AMIDINO GROUP SUBSTITUTED HETEROCYCLIC DERIVATIVES AND THEIR USE AS ANTICOAGULANTS | AXYS PHARMACEUTICALS, INC. (US) | 1999-06-03 | — | — | WO | disclosed |