Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855489 | 0.83 | ERN1 (0.74) | ERN1 | |
| SCHEMBL14091645 | 0.83 | ERN1 (0.74) | ERN1 | |
| SCHEMBL6644961 | 0.78 | ERN1 (0.62) | ERN1 | |
| SCHEMBL5796324 | 0.77 | ALDH1A1 (0.49) | ERN1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL30352601 | 0.76 | ALDH1A1 (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL498127 | 0.76 | ALDH1A1 (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7411191 | 0.76 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DFPR2 | |
| SCHEMBL6639272 | 0.73 | ERN1 (0.74) | ERN1 | |
| SCHEMBL24254372 | 0.73 | ERN1 (0.60) | ERN1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL20456502 | 0.73 | ERN1 (0.42) | ERN1PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995027692-A1 | SUBTITUTED BIPHENYL TNF INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-10-19 | — | — | WO | disclosed |