Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 5/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417660 | 0.90 | RB1 (0.53) | RB1NR2E1VCPCHRNA7SIGMAR1 | |
| SCHEMBL7411272 | 0.89 | RB1 (0.52) | RB1NR2E1VCPKDM4EHSD17B10 | |
| SCHEMBL7405425 | 0.88 | RB1 (0.51) | RB1NR2E1VCPCHRNA7 | |
| SCHEMBL7409212 | 0.88 | RB1 (0.51) | RB1NR2E1VCPCHRNA7KDM4E | |
| SCHEMBL7409258 | 0.87 | RB1 (0.50) | RB1NR2E1VCPCHRNA7 | |
| SCHEMBL7409934 | 0.85 | RB1 (0.51) | RB1NR2E1VCP | |
| SCHEMBL7412987 | 0.82 | RB1 (0.47) | RB1NR2E1VCPCHRNA7 | |
| SCHEMBL7410027 | 0.80 | VCP (0.50) | RB1NR2E1VCP | |
| SCHEMBL7410031 | 0.80 | RB1 (0.46) | RB1NR2E1VCP | |
| SCHEMBL7408834 | 0.79 | RB1 (0.55) | RB1NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |