Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RB1 | P06400 | 4/20 | 0.52 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417660 | 0.99 | RB1 (0.53) | RB1NR2E1SIGMAR1VCPBCHE | |
| SCHEMBL7405425 | 0.90 | RB1 (0.51) | RB1NR2E1VCP | |
| SCHEMBL7409212 | 0.90 | RB1 (0.51) | RB1NR2E1VCPKDM4E | |
| SCHEMBL7409258 | 0.89 | RB1 (0.50) | RB1NR2E1VCP | |
| SCHEMBL7408196 | 0.89 | RB1 (0.50) | RB1NR2E1SIGMAR1VCPKDM4E | |
| SCHEMBL7409934 | 0.87 | RB1 (0.51) | RB1NR2E1VCPMAPT | |
| SCHEMBL7412987 | 0.84 | RB1 (0.47) | RB1NR2E1VCP | |
| SCHEMBL7410027 | 0.82 | VCP (0.50) | RB1NR2E1VCPMAPT | |
| SCHEMBL7408834 | 0.81 | RB1 (0.55) | RB1NR2E1 | |
| SCHEMBL7410031 | 0.80 | RB1 (0.46) | RB1NR2E1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |