SCHEMBL7408583

SCHEMBL7408583

O=[N+]([O-])c1ccc(S(=O)(=O)Cl)c(Br)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.44
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA9 Q16790 3/20 0.44
CA5A P35218 2/20 0.44
CA14 Q9ULX7 2/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA7 P43166 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PTPRC P08575 1/20 0.43
S100A4 P26447 1/20 0.43
ALDH1A1 P00352 7/20 0.42
CYP3A4 P08684 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
PDE7A Q13946 2/20 0.41
PDE2A O00408 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31449980 1.00 CA2 (0.44) CA2CA12CA1CA9CA5A
SCHEMBL29538993 0.86 PTPRC (0.47) CA2CA12CA1CA9CA5A
SCHEMBL3810591 0.86 PTPRC (0.47) CA2CA12CA1CA9CA5A
SCHEMBL12496253 0.82 ALDH1A1 (0.46) CA2CA12CA1CA9CA5A
SCHEMBL18844776 0.82 NT5E (0.50) CA2CA12CA1CA9CA5A
SCHEMBL17259 0.80 ALDH1A1 (0.56) CA2CA12CA1CA9HSD17B10
SCHEMBL29430338 0.80 ALDH1A1 (0.56) CA2CA12CA1CA9HSD17B10
SCHEMBL1817485 0.80 HSD17B10 (0.60) HSD17B10PTPRCS100A4ALDH1A1TDP1
SCHEMBL31518627 0.80 HSD17B10 (0.60) HSD17B10PTPRCS100A4ALDH1A1TDP1
SCHEMBL12496147 0.79 ALDH1A1 (0.43) CA2CA12CA1CA9CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0384276-B1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AG (DE) 1993-11-10 EP disclosed
EP-0384276-A1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed
US-4257952-A PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES STERLING DRUG INC. (US) 1981-03-24 US disclosed
US-4172834-A ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS STERLING DRUG INC. (US) 1979-10-30 US disclosed
US-4062864-A ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1977-12-13 US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 US disclosed