Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057032 | 0.79 | — | — | |
| SCHEMBL7410277 | 0.77 | TSHR (0.40) | — | |
| SCHEMBL5286240 | 0.73 | ACHE (0.40) | CA1CA2 | |
| SCHEMBL12168594 | 0.71 | TAAR1 (0.44) | CA2 | |
| SCHEMBL1128391 | 0.71 | MMP2 (0.41) | CA1CA2 | |
| SCHEMBL121680 | 0.70 | KCNH2 (0.35) | CA1CA2 | |
| SCHEMBL17625233 | 0.68 | TSHR (0.41) | — | |
| SCHEMBL97582 | 0.68 | CA1 (0.52) | CA1CA2 | |
| SCHEMBL10350900 | 0.67 | CA1 (0.32) | CA1CA2 | |
| SCHEMBL17625239 | 0.65 | TDP1 (0.36) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005446-A1 | N-AROYLPHENYLALANINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999010313-A1 | N-AROYLPHENYLALANINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1999-03-04 | — | — | WO | disclosed |