Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4612352 | 0.84 | KMT2A (0.58) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL20825600 | 0.82 | KMT2A (0.56) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL27081834 | 0.80 | CASP3 (0.52) | KMT2ACASP3TLR2 | |
| SCHEMBL16724665 | 0.80 | KMT2A (0.48) | KMT2AEPHX2CASP3TLR2 | |
| SCHEMBL19358192 | 0.79 | KMT2A (0.59) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL16744160 | 0.79 | TLR2 (0.53) | CASP3TLR2 | |
| SCHEMBL16744142 | 0.79 | TLR2 (0.53) | CASP3TLR2 | |
| SCHEMBL28528205 | 0.79 | KMT2A (0.58) | KMT2AEPHX2CASP3FABP7FABP5 | |
| SCHEMBL8236471 | 0.78 | KMT2A (0.70) | KMT2AEPHX2 | |
| SCHEMBL1147745 | 0.77 | KMT2A (0.47) | KMT2AEPHX2CASP3TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828737-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037492-A1 | ISOXAZOLINE AND ISOXAZOLE DERIVATIVES AS INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-11-28 | — | — | WO | disclosed |