Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.39 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743573 | 0.92 | HTR6 (0.42) | HTR6HTR2CHTR2ADRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL743912 | 0.88 | HTR6 (0.46) | HTR6HTR2CHTR2ADRD3CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL743495 | 0.87 | HTR6 (0.47) | HTR6HTR2CHTR2ACYP3A4HTR2B | |
| Trifluoroacetic Acid SCHEMBL743367 | 0.87 | HTR6 (0.47) | HTR6HTR2CHTR2ACYP3A4HTR2B | |
| Trifluoroacetic Acid SCHEMBL743534 | 0.86 | HTR6 (0.41) | HTR6HTR2CHTR2ADRD3CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL743994 | 0.86 | HTR6 (0.46) | HTR6HTR2CHTR2ACYP3A4HTR2B | |
| Trifluoroacetic Acid SCHEMBL743618 | 0.85 | HTR6 (0.49) | HTR6HTR2CCYP3A4 | |
| Trifluoroacetic Acid SCHEMBL742682 | 0.85 | HTR6 (0.43) | HTR6HTR2CHTR2ACYP3A4HTR2B | |
| Trifluoroacetic Acid SCHEMBL743110 | 0.84 | HTR6 (0.41) | HTR6HTR2CHTR2ACYP3A4HTR2B | |
| Trifluoroacetic Acid SCHEMBL744053 | 0.83 | HTR6 (0.46) | HTR6HTR2CHTR2ACYP3A4HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138333-B2 | Sulfonyl-indole derivatives | PROXIMAGEN LIMITED (GB) | 2012-03-20 | — | — | US | disclosed |
| US-20080293694-A1 | New compounds | BIOVITRUM AB (PUBL.) (SE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293694-A1 | New compounds | HTR6, HTR1A, HTR1B | HTR6 1/4885HTR2C 8/4885HTR2A 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.