Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408714 | 1.00 | PRMT1 (0.49) | PRMT1GAAGFERALDH1A1MAPT | |
| SCHEMBL9689658 | 0.86 | KMT2A (0.49) | PRMT1GAAALDH1A1MAPTTDP1 | |
| SCHEMBL10409069 | 0.86 | KMT2A (0.49) | PRMT1GAAALDH1A1MAPTTDP1 | |
| SCHEMBL4715718 | 0.85 | TLR4 (0.51) | GAAALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL4715716 | 0.85 | TLR4 (0.51) | GAAALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL10535536 | 0.82 | CCNB2 (0.46) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL10535540 | 0.82 | CCNB2 (0.46) | GAAMAPTTDP1MEN1KMT2A | |
| SCHEMBL11836212 | 0.81 | ALDH1A1 (0.56) | GAAALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL11836225 | 0.81 | ALDH1A1 (0.56) | GAAALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL7298528 | 0.81 | TSHR (0.50) | GAAALDH1A1MAPTTDP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| US-5212195-A | Substituted indole antagonists derivatives which are angiotensin II | SYNTEX (U.S.A.) INC. (US) | 1993-05-18 | — | — | US | disclosed |