Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.48 |
| ▸ | QDPR | P09417 | 3/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KHK | P50053 | 3/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31752730 | 0.87 | HTR2C (0.62) | HTR2CQDPRSIGMAR1KHKHTR7 | |
| SCHEMBL6434221 | 0.87 | HTR2C (0.62) | HTR2CQDPRSIGMAR1KHKHTR7 | |
| Trifluoroacetic Acid SCHEMBL29968193 | 0.85 | HTR2C (0.48) | HTR2CQDPRP2RY14SIGMAR1NAMPT | |
| Trifluoroacetic Acid SCHEMBL16799644 | 0.83 | HTR2C (0.71) | HTR2CQDPRP2RY14SIGMAR1HTR7 | |
| Trifluoroacetic Acid SCHEMBL30745997 | 0.79 | P2RY14 (0.41) | HTR2CQDPRP2RY14SIGMAR1KHK | |
| Trifluoroacetic Acid SCHEMBL29803385 | 0.79 | QDPR (0.41) | HTR2CQDPRP2RY14SIGMAR1SOS1 | |
| Trifluoroacetic Acid SCHEMBL19989664 | 0.79 | SIGMAR1 (0.67) | HTR2CQDPRP2RY14SIGMAR1HTR7 | |
| Trifluoroacetic Acid SCHEMBL30182435 | 0.78 | QDPR (0.53) | HTR2CQDPRP2RY14SIGMAR1KHK | |
| Trifluoroacetic Acid SCHEMBL30745987 | 0.78 | P2RY14 (0.40) | HTR2CQDPRP2RY14SIGMAR1KHK | |
| Trifluoroacetic Acid SCHEMBL29749858 | 0.76 | QDPR (0.50) | HTR2CQDPRP2RY14SIGMAR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036062-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | Pfizer Limited (GB) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999029667-A1 | HYDROXAMIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE (MMP) INHIBITORS | PFIZER LIMITED (GB) | 1999-06-17 | — | — | WO | disclosed |