Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | VPS4B | O75351 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | APOL1 | O14791 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407947 | 0.91 | HTR1F (0.41) | HTR6HTR1FHTR1DHTR1BVPS4B | |
| SCHEMBL7416193 | 0.89 | HTR1F (0.36) | HTR6HTR1FHTR1DHTR1BDPP4 | |
| SCHEMBL7411041 | 0.88 | GRIN2B (0.41) | HTR6HTR1FHTR1DHTR1B | |
| Iodomethane SCHEMBL7409589 | 0.86 | GRIN2B (0.40) | HTR6HTR1FHTR1DHTR1B | |
| SCHEMBL7404550 | 0.84 | SPHK1 (0.36) | HTR1FHTR1DHTR1BHTR1A | |
| SCHEMBL7409892 | 0.82 | HTR1D (0.44) | HTR1DHTR1B | |
| SCHEMBL7414227 | 0.81 | SLC6A2 (0.38) | HTR6HTR1FDPP4DPP9DPP7 | |
| SCHEMBL7408841 | 0.81 | HTR1F (0.45) | HTR6HTR1FHTR1DHTR1BVPS4B | |
| SCHEMBL7407176 | 0.81 | HTR1F (0.39) | HTR6HTR1FDPP4DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL7406784 | 0.80 | HTR1F (0.39) | HTR6HTR1FDPP4DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |