Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR1F | P30939 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 4/20 | 0.33 |
| ▸ | HTR1B | P28222 | 4/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7411041 | 0.98 | GRIN2B (0.41) | GRIN2BHTR6DRD2DRD3HTR1F | |
| SCHEMBL7407947 | 0.91 | HTR1F (0.41) | HTR6DRD2HTR1FCYP2D6CHRM1 | |
| SCHEMBL7416193 | 0.89 | HTR1F (0.36) | GRIN2BHTR6HTR1FPTGDR2HTR1D | |
| SCHEMBL7414227 | 0.86 | SLC6A2 (0.38) | GRIN2BHTR6HTR1F | |
| SCHEMBL7408792 | 0.86 | HTR6 (0.38) | HTR6HTR1FHTR1DHTR1B | |
| SCHEMBL11351375 | 0.85 | CCR3 (0.40) | HTR6HTR1FPTGDR2 | |
| SCHEMBL7404550 | 0.84 | SPHK1 (0.36) | DRD2DRD3HTR1FHTR1DHTR1B | |
| SCHEMBL7409892 | 0.81 | HTR1D (0.44) | HTR1DHTR1B | |
| SCHEMBL7403609 | 0.81 | CHRM4 (0.37) | HTR1F | |
| SCHEMBL7407176 | 0.80 | HTR1F (0.39) | GRIN2BHTR6DRD2DRD3HTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |