Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 11/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7407893 | 0.90 | PLAU (0.48) | SLC16A3GPR27F2F10PRSS1 | |
| SCHEMBL7413497 | 0.85 | SLC16A3 (0.52) | SLC16A3GPR27F2F10PRSS1 | |
| SCHEMBL7409765 | 0.85 | NPC1 (0.46) | SLC16A3F2PRSS1GAA | |
| SCHEMBL7411588 | 0.85 | ALDH1A1 (0.47) | SLC16A3ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7411350 | 0.84 | GPR27 (0.51) | SLC16A3GPR27F2F10PRSS1 | |
| SCHEMBL7407982 | 0.80 | SLC16A3 (0.50) | SLC16A3GPR27KAT6AALDH1A1LMNA | |
| SCHEMBL7411994 | 0.78 | PLAU (0.55) | GPR27F2F10PRSS1PRSS2 | |
| SCHEMBL8415881 | 0.77 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7407140 | 0.74 | PLAU (0.50) | SLC16A3GPR27F2F10PRSS1 | |
| SCHEMBL7409768 | 0.74 | ALDH1A1 (0.48) | F10ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999042439-A1 | NOVEL THIOBENZAMIDES | ROCHE DIAGNOSTICS GMBH (DE) | 1999-08-26 | — | — | WO | disclosed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |