SCHEMBL7409072

SCHEMBL7409072

CCCCOC(=O)N[C@@H](CNC(=O)C[C@H]1CC(c2ccc(C=NON)cc2)=NO1)C(=O)OC

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 20/20 0.73
ITGA2B P08514 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7213402 0.86 ITGB3 (0.77) ITGB3ITGA2B
SCHEMBL7220986 0.85 ITGB3 (0.83) ITGB3ITGA2B
Roxifiban SCHEMBL24336949 0.85 ITGB3 (1.00) ITGB3ITGA2B
Roxifiban SCHEMBL344302 0.85 ITGB3 (1.00) ITGB3ITGA2B
SCHEMBL7217243 0.84 ITGB3 (0.76) ITGB3ITGA2B
SCHEMBL7214664 0.84 ITGB3 (0.76) ITGB3ITGA2B
SCHEMBL7214752 0.84 ITGB3 (0.76) ITGB3ITGA2B
SCHEMBL7413714 0.83 ITGB3 (0.80) ITGB3ITGA2B
SCHEMBL7407564 0.83 ITGB3 (0.80) ITGB3ITGA2B
Roxifiban SCHEMBL919675 0.83 ITGB3 (0.95) ITGB3ITGA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023274-A1 AN EFFICIENT METHOD FOR THE CONVERSION OF NITRILES TO AMIDINES Du Pont Pharmaceuticals Company (US) 2000-08-02 EP disclosed
WO-1999018090-A1 AN EFFICIENT METHOD FOR THE CONVERSION OF NITRILES TO AMIDINES BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 1999-04-15 WO disclosed